Abstract
Clinicopathological and immunohistochemical profile of poorly differentiated neoplasms of stomach and intestine - IJPO- Print ISSN No: - 2394-6784 Online ISSN No:- 2394-6792 Article DOI No:- 10.18231/2394-6792.2019.0013, Indian Journal of Pathology and Oncology-Indian J Pathol Oncol
Highlights
The aim of this study was to review the clinicopathological and immunohistochemical features of poorly differentiated neoplasms of gastric and intestinal region, reported in a tertiary care hospital, for a period of two years
Materials and Methods This prospective study was conducted in the Department of Pathology in a tertiary care hospital, Chennai after approval from the institutional ethics committee
Since the histological type of each and every tumor is important for assessing staging, treatment protocols and prognosis, it highlights the strong role of pathologists who should use all available resources and recent advances, along with light microscopy to arrive at a definitive final diagnosis
Summary
The aim of this study was to review the clinicopathological and immunohistochemical features of poorly differentiated neoplasms of gastric and intestinal region, reported in a tertiary care hospital, for a period of two years. Among the total of 454 cases of gastrointestinal malignancies, 60 cases were poorly differentiated malignancies (PDM) of stomach and intestine and were included in the study. Of the 60 cases of poorly differentiated malignancies of gastric and intestinal region, 46 cases were poorly differentiated adenocarcinomas (PDAC), 12 cases were non-Hodgkins lymphomas (NHL) and 2 cases were neuroendocrine carcinomas (NEC). Gastrointestinal malignancies include a wide variety of tumors. Almost each and every type of gastrointestinal malignancies have near identifiable immunohistochemical signatures, which helps in appropriate diagnoses and there by very useful for optimum treatment procedures
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