Abstract
A 9-year-old girl was born with cutaneous erythema and plaques on the left side of the body as well as deformity of the left lower limb.Physical examination revealed limp,obvious shortening of the left lower limb,deformity of the second,third and fourth toes of the left foot.Both muscle tone and muscle strength were decreased in the left lower limb compared with the right lower limb.Cutaneous examination showed erythematous hypertrophic plaques in the left posterior neck,buttock,perineum,leg,and foot.Histopathologic examination of the skin lesions showed epidermal hyperkeratosis,a small number of foamy cells infiltrating the dermal papillae,as well as focal lymphocyte and plasma cell infiltrates in the superficial dermis.Moreover,the foamy cells in the dermal papillae stained strongly positive for CD68 and CD163,but negative for S100.A diagnosis of CHILD syndrome was made. Key words: CHILD syndrome ; Pathology; Immunohistochemistry
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