Abstract
BackgroundThis study was carried out to establish the relative incidence and provide clinico-pathologic information on the various histological types of ameloblastoma seen at the Obafemi Awolowo University Teaching Hospital complex, Ile-Ife in order to provide a baseline data which will be of significance to the pathologist and clinician.MethodsClinico-pathologic data on a total of 77 histologically diagnosed cases of ameloblastoma archieved at the Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife over a 15 year period were obtained and analysed descriptively.ResultsFollicular ameloblastoma was the most common histological type (50 cases, 64.9%), followed by plexiform ameloblastoma (10 cases, 13.0%). 4 (5.2%) cases of desmoplastic and 3 (3.9%) cases of acanthomatous ameloblastoma were seen while the basal cell variant accounted for 2 (2.6%) cases. Only 1 case of the unicystic type was seen. Some of the 77 cases presented as a mixture of two or more histological types. Ameloblastoma occurred over an age range of 11 to 70 years with a peak age incidence in the 3rd decade.ConclusionThis study provides a baseline data on variants of ameloblastoma as obtained in a suburban Nigerian population. Since variants of ameloblastoma differ in biologic behaviour, the data collected in this study provides clinicopathologic information which is of significance to the pathologist and clinician.
Highlights
This study was carried out to establish the relative incidence and provide clinicopathologic information on the various histological types of ameloblastoma seen at the ObafemiAwolowo University Teaching Hospital complex, Ile-Ife in order to provide a baseline data which will be of significance to the pathologist and clinician
This study provides a baseline data on variants of ameloblastoma as obtained in a suburban Nigerian population
Since variants of ameloblastoma differ in biologic behaviour, the data collected in this study provides clinicopathologic information which is of significance to the pathologist and clinician
Summary
Awolowo University Teaching Hospital complex, Ile-Ife in order to provide a baseline data which will be of significance to the pathologist and clinician. Ameloblastoma is a neoplasm of odontogenic epithelium, especially of enamel organ-type tissue that has not undergone differentiation to the point of hard tissue formation [1]. It generally occurs in bone, and it has been postulated that the epithelium of origin is derived from one of the following sources: (1) cell rests of the enamel organ, (2) epithelium of odontogenic cysts, (3) disturbances of the developing enamel organ, (4) basal cells of the surface epithelium or (5) heterotropic epithelium in other parts of the body [2]. Haematoxylin and eosin stained sections of the ameloblastomas were retrieved and reviewed in order to reconfirm the diagnosis and where necessary, revise the diagnosis in light of available clinical and histological details and the WHO histological typing of odontogenic tumours[4]
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