Abstract
Objective To analyze the clinicopathological features of gastric stromal tumor with primary gastrointestinal carcinoma. Methods 469 cases of gastrointestinal stromal tumor (GIST) from January 2011 to December 2014 admitted to PLA General Hospital were retrospectively analyzed. Gastric stromal tumor patients with primary gastrointestinal carcinoma were screened. The concomitant gastrointestinal cancer site, stromal tumor size, mitotic activity, immunohistochemistry were also detected. Results The gastric stromal tumor with primary gastrointestinal carcinoma accounted for 14.7 % (69/469) of all the GIST, in which the small gastric stromal tumor accounted for 65.2 % (45/69) of the total and 9.59 % (45/469) of all the GIST. The diameter of all tumors was < 5 cm, and the mitotic was < 5/50 HPF. The positive rates of CD117, CD34, DOG-1 were 92.8 % (64/69), 92.8 % (64/69), 94.1 % (65/69). The Fletcher was classified as low-risk and extreme low-risk. Conclusions Gastric stromal tumor with primary gastrointestinal carcinoma has no specific clinical features and pathological immunohistochemical markers. Its malgnant degree is lower than GIST. Its prognosis is associated with primary gastrointestinal cancer staging. Key words: Gastrointestinal stromal tumors; Small gastric stromal tumor; Primary gastrointestinal tract neoplasms
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.