Clinicopathological analysis of abnormal uterine bleeding in reproductive and post menopausal women in a tertiary care centre of south eastern part of India

Abstract

Abnormal uterine bleeding (AUB) is a common presentation of gynecologic disorder in Tropical countries like India. Though various underlying causes exists, endometrial pathology is the major reason for AUB and histopathological evaluation of endometrial biopsy samples remains main stay for diagnosis. To analyse the clinico-pathological spectrum of abnormal uterine bleeding with associated endometrial lesions in patients presenting to a tertiary care hospital in south eastern part of India Patients presenting to gynaecology OPD with AUB as presenting complaints were evaluated with Dilatation & curettage and the endometrial samples obtained were analysed for histopathological evaluation Among 153 cases studied for a period of 2 years duration, majority of cases were non-neoplastic lesions (n=93) followed neoplastic lesions (n=60). Proliferative and secretory endometrium was the common condition among reproductive age group. Malignancy was predominantly noted among post menopausal age group and adenocarcinoma (TypeI) was the common endometrial malignancy noted The incidence of Abnormal uterine bleeding was higher than assumed among the study population and histopathological evaluation of endometrial biopsy samples serves as a mainstay in diagnosis and also in categorizing the underlying etiology.