Abstract
Metastases to lymphnodes, lymphangitic invasion and the mode of spread of carcinoma into mucosal layer are the most important factors influencing on the prognosis of early gastric cancer. Two hundred and ninetythree cases of early gastric cancer were studied, all of which received surgical resection during the period from January 1965 to November 1982. They were investigated according to clinicopathologic factors and compared between m-group and sm-group. The sm group were further divided into the following three subtypes; 1) slight infiltrative type which has minute and partial submucosal invasion (sm1), 2) moderate infiltrative type which is an intermediated type and has invasion down to the mid-submucosal layer (sm2), and 3) deep infiltrative type which has deep and massive invasion almost adjacent to the proper muscle (sm3).The results obtained were as follows : 1) Metastasis to lymphnodes was present in 2.2% of the patients of sm1 and in 16.4% of the patients of sm2, and in 58% of the patients of sm3.2) Lymphangitic invasion was noted in 14.9% of sm1, in 39% of sm2 and in 75% of sm3.3) The prognosis of sm-group were influenced by the presence of metastasis to lymphnodes and lymphangitic invasion. The survial rate of such cases was about 70% at ten years.
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