Abstract
IntroductionParotid carcinomas have varying histological types and diverse biologic behaviors. Establishing an adequate treatment plan and predicting recurrence is important.ObjectiveTo analyze the risk factors associated with recurrence in our 5 year experience with 30 cases of primary parotid carcinoma undergoing surgery at a single institute.MethodsFrom January 2009 to December 2013, 30 patients with surgical treatment of parotid carcinoma were identified based on their medical records.ResultsThe 30 patients were comprised of 17 males and 13 females. Among 11 patients with T4 tumors, seven patients had recurrence. Among seven patients with cervical nodal metastasis, all patient except one had recurrence. Clinically late stages (stage III and IV) showed more common recurrence than early stage (stage I and II) lesions. Lymphovascular invasion was seen in 5 patients, and all patients had recurrence. Among 11 patients with extracapsular spread, 7 patients had recurrence. In 17 patients with high grade carcinomas, ten patients had recurrence. In 13 patients with low grade carcinomas, no patients experienced recurrence.ConclusionT- and N-stage, clinical stage, lymphovascular invasion, extracapsular spread, and histopathologic grade correlate significantly with recurrence in parotid carcinoma.
Highlights
Parotid carcinoma is an uncommon malignancy and constitutes 1%---3% of all head and neck cancers.1---5 Parotid carcinomas have varying histological types and diverse biologic behaviors.1---5 Treatment of parotid carcinoma remains challenging because of its relative rarity, unpredictable biological behavior, and risk of recurrence.[1,2,5,6]establishing an adequate treatment plan and predicting recurrence is important.[5]
The remaining two patients were incidentally diagnosed by PET-computed tomography (CT)
Previous studies have suggested several clinical and histological factors associated with recurrence of parotid carcinoma, such as TNM staging system, clinical stage, perineural or lymphovascular invasion, extracapsular spread, positive surgical margin, and histological grade.1,4,5,8---12
Summary
Parotid carcinoma is an uncommon malignancy and constitutes 1%---3% of all head and neck cancers.1---5 Parotid carcinomas have varying histological types and diverse biologic behaviors.1---5 Treatment of parotid carcinoma remains challenging because of its relative rarity, unpredictable biological behavior, and risk of recurrence.[1,2,5,6]establishing an adequate treatment plan and predicting recurrence is important.[5]. Parotid carcinoma is an uncommon malignancy and constitutes 1%---3% of all head and neck cancers.1---5. Parotid carcinomas have varying histological types and diverse biologic behaviors.1---5. Treatment of parotid carcinoma remains challenging because of its relative rarity, unpredictable biological behavior, and risk of recurrence.[1,2,5,6]. Establishing an adequate treatment plan and predicting recurrence is important.[5] In general, surgery is the treatment of choice for all parotid tumors and postoperative radiotherapy (RT) is applied as supplementary treatment.2,4---6. There have been few published reports about predicting recurrence.[5] The identification of factors associated with recurrence is of paramount relevance for treatment of parotid carcinomas
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