Abstract

Toxocariasis is one of the commonest zoonosis parasites worldwide, particularly in sheep-raisingcountries. Epilepsy is an important health problem in developing countries. The study assessed theseropositivity of toxocariasis in Egyptian idiopathic epileptic children. A case-control study was conductedon 125 children (1-18 years) with idiopathic epilepsy (patients) and 72 non-epileptic normalchildren (controls). All children underwent history taking, clinical examination, lab investigations,ELISA, and WB seropositivity to detect toxocariasis.The results showed no significant difference in age, sex, and socioeconomic level, but a significantdifference was in residence and pet dogs between patients and controls (p < 0.05). Also, the Toxocarainfection (ELISA) among patients was 41.6% versus 23.6% among controls and (Immunoblotting)17.6% versus 5.5% respectively. There was an association between toxocariasis and epilepsy, withsignificant difference between patients and controls (P<0.05). Seropositivity was more in epilepticwith generalized than partial seizures (p=0.06). As risk factors, residence and eating raw/undercookedmeat showed significant difference and pet dogs and soil contact showed a highly significant differencein toxocariasis seropositive patients (P<0.05).

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