Abstract
The World Health Organization (WHO) Classification of Central Nervous System describes several types of glioneuronal tumors, which are known to induce refractory partial seizures in children and adults [1]. The most frequent ones are Dysembryoplastic Neuroepithelial Tumors (DNETs) [2], gangliogliomas and oligodendrogliomas, but other types of complex glioneuronal lesions can be observed and are described as Low-Grade Epilepsy Associated Neuroepithelial Tumors (LEAT).
Highlights
The World Health Organization (WHO) Classification of Central Nervous System describes several types of glioneuronal tumors, which are known to induce refractory partial seizures in children and adults [1]
The angiocentric glioma, previously known as Angiocentric Neuroepithelial Tumor (ANET), is one of the rarest of glioneuronal tumors. We report this rare entity in a 10-year-old child who underwent surgery for refractory epilepsy
Pathology revealed an angiocentric glioma with elongated monomorphic spindle-shaped glial cells presenting a perivascular distribution (Figure 2A), positive for glial fibrillary acidic protein Glial Fibrillary Acidic Protein (GFAP) (Figure 2B) and epithelial membrane antigen Epithelial Membrane Antigen (EMA) (Figure 2C)
Summary
The World Health Organization (WHO) Classification of Central Nervous System describes several types of glioneuronal tumors, which are known to induce refractory partial seizures in children and adults [1]. Clinico-Radiological Presentation of Angiocentric Neuroepithelial Tumor Associated with Pharmacoresistant Epilepsy: A Case Report Refractory tumor-related epilepsy, Low-grade epilepsy associated neuroepithelial tumors, Angiocentric glioma
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