Abstract
Background: Lung cancer is currently the most frequently diagnosed cancer in the world and the number one cause of cancer mortality worldwide.Materials and Methods: A descriptive study was conducted in 55 diagnosed lung carcinoma cases being treated in a Kathmandu based hospital over a period of 18 months from 22nd Oct. 2012 to 21st April 2014.Results: Out of total 55 lung carcinoma cases, 33 patients were male and 22 were female with Male: Female ratio of 1.5:1. The most frequent age group was 71-80 years. Lung cancer was more common among smokers (52.73 % of cases). Out of 47.27% non smokers, 76.92% were female. Squamous cell carcinoma was found to be the most common cancer type, comprising 63.64% of cases followed by adenocarcinoma (29.09% of cases) and small cell carcinoma (7.27% of cases). Among various diagnostic methods, CT guided Fine needle aspiration cytology (FNAC) and Pleural fluid cytology was found to be the best methods.Conclusion: Smoking showed a positive correlation among carcinoma of lung patients. Squamous cell carcinoma and adenocarcinoma were the most common tumors encountered among the smokers and non-smokers respectively. CT guided Fine needle aspiration cytology (FNAC) and Pleural fluid cytology yields the most diagnostic materials.DOI: http://dx.doi.org/3126/jpn.v4i8.11496 Journal of Pathology of Nepal; Vol4, No.8 (2014) 623-625Background: Lung cancer is currently the most frequently diagnosed cancer in the world and the number one cause of cancer mortality worldwide.Materials and Methods: A descriptive study was conducted in 55 diagnosed lung carcinoma cases being treated in a Kathmandu based hospital over a period of 18 months from 22nd Oct. 2012 to 21st April 2014.Results: Out of total 55 lung carcinoma cases, 33 patients were male and 22 were female with Male: Female ratio of 1.5:1. The most frequent age group was 71-80 years. Lung cancer was more common among smokers (52.73 % of cases). Out of 47.27% non smokers, 76.92% were female. Squamous cell carcinoma was found to be the most common cancer type, comprising 63.64% of cases followed by adenocarcinoma (29.09% of cases) and small cell carcinoma (7.27% of cases). Among various diagnostic methods, CT guided Fine needle aspiration cytology (FNAC) and Pleural fluid cytology was found to be the best methods.Conclusion: Smoking showed a positive correlation among carcinoma of lung patients. Squamous cell carcinoma and adenocarcinoma were the most common tumors encountered among the smokers and non-smokers respectively. CT guided Fine needle aspiration cytology (FNAC) and Pleural fluid cytology yields the most diagnostic materials.DOI: 3126/jpn.v4i8.11496 Journal of Pathology of Nepal; Vol4, No8(2014)
Highlights
Overall the lung cancer is the most commonly diagnosed cancer comprising 1.69 million (13.3%) out of 12.7 million new cancer cases
The patients with lung carcinoma presents with symptom like cough, hemoptysis, wheeze, shortness of breath and pain.[4]
Out of 55 diagnosed cases of lung carcinoma being treated in the study period, 60% patients were male and 40% were female with male to female ratio of 1.5:1
Summary
Overall the lung cancer is the most commonly diagnosed cancer comprising 1.69 million (13.3%) out of 12.7 million new cancer cases. It was found to have high mortality rate of 18.2% (1.38 million out of 7.6 million cancer deaths) in 2008.1 The less developed regions of the world were the most commonly affected comprising 56% of the new cancer cases and 63% of the cancer death.[1] Since 1987, more women have died each year of lung cancer than of the breast. Correspondence: Commonly the patients with lung carcinoma presents with symptom like cough, hemoptysis, wheeze, shortness of breath and pain.[4] for the diagnosis investigations are required among which X-ray chest is one of the first investigative step.[3] Others include CT imaging and cytological examination of sputum, pleural fluid, alveolar lavage, bronchial brushing and CT guided Fine needle aspiration cytology (FNAC) and Biopsy.[5]. Lung cancer is currently the most frequently diagnosed cancer in the world and the number one cause of cancer mortality worldwide
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