Abstract

Background: The aim of the study was to study the clinical profile, laboratory parameters of enteric fever cases in pediatric age group.
 Methods: This was a prospective study carried on Pediatric patients aged 1 to 14 years with clinically suspected enteric fever (fever for 5 days or more with no primary focus on clinical examination) and proven either by positive blood culture or Widal test with significant titre (level of both H or O antibodies of 1 in 160 dilution or more by tube method) were enrolled in the study.
 Results: The mean white blood cell (WBC) count was 8256.32±1236.12 cells/cumm. Out of 100 patients, 73(73.00%) had WBC count within the normal range (4000-11000 cells/cumm). 3(3.00%) had leucopenia, while 24(24.00%) had leucocytosis. 4(4.00%) patients had thrombocytopenia
 Conclusions: Enteric fever is major cause of febrile illness in children (especially school going). Fever with abdominal pain, vomiting and diarrhea were major clinical manifestations. There was 100% sensitivity to ceftriaxone, which was highly effective as monotherapy.
 Keywords: WBC, Typhoid, Clinical profile.

Highlights

  • Enteric fever is a systemic bacterial infection caused by Salmonella enteric serotype Typhi or Paratyphi A or B

  • Background: The aim of the study was to study the clinical profile, laboratory parameters of enteric fever cases in pediatric age group. This was a prospective study carried on Pediatric patients aged 1 to 14 years with clinically suspected enteric fever and proven either by positive blood culture or Widal test with significant titre were enrolled in the study

  • Out of 100 patients, 73(73.00%) had white blood cell (WBC) count within the normal range (4000-11000 cells/cumm). 3(3.00%) had leucopenia, while 24(24.00%) had leucocytosis. 4(4.00%) patients had thrombocytopenia Conclusions: Enteric fever is major cause of febrile illness in children

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Summary

Introduction

Enteric fever is a systemic bacterial infection caused by Salmonella enteric serotype Typhi or Paratyphi A or B. Enteric fever is the most common cause of fever lasting for more than 7 days in clinical practice in India. 1. The aim of the study was to study the clinical profile, laboratory parameters of enteric fever cases in pediatric age group. Methods: This was a prospective study carried on Pediatric patients aged 1 to 14 years with clinically suspected enteric fever (fever for 5 days or more with no primary focus on clinical examination) and proven either by positive blood culture or Widal test with significant titre (level of both H or O antibodies of 1 in 160 dilution or more by tube method) were enrolled in the study. 4(4.00%) patients had thrombocytopenia Conclusions: Enteric fever is major cause of febrile illness in children (especially school going). Fever with abdominal pain, vomiting and diarrhea were major clinical manifestations.

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