Abstract
Background: Pancytopenia is a relatively common hematological entity. It may result from relatively benign causes such as viral infections and vitamin B12/folic acid deciency to more fatal bone marrow aplasia and leukaemias. The severity of pancytopenia and the underlying pathology determine the management and prognosis. Objectives: To study the etiology and clinic-hematological prole in patients of peripheral blood pancytopenia. Materials And Methods: This was a retrospective study conducted at G S Medical College, Hapur and Noida international institute of Medical Sciences Greater Noida, during the period of November 2017 to November 2020 Results: A total of 192 patients (103 males and 89 females) were diagnosed to have pancytopenia. Most of the patients presented with generalized weakness and fever. The commonest physical nding was pallor, followed by splenomegaly. The various causes of pancytopenia included infections(n=132), megaloblastic anaemia (MA)(n=46), drugs, aplastic anaemia and subleukaemic leukaemia. We found a signicant association between megaloblastic anaemia and pancytopenia. Conclusion: The present study concluded that infection and megaloblastic anaemia are the most common cause of pancytopenia. The more serious disorders affecting the bone marrow constitute only <5% of all cases of pancytopenia.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
