CLINICO-DEMOGRAPHIC STUDY OF PATIENTS WITH ACANTHOSIS NIGRICANS

Abstract

Introduction- Acanthosis Nigricans (AN) is a fairly common skin pigmentary disorder .AN is characterized by dark, coarse and thickened skin with a velvety texture, being symmetrically distributed on the neck, the axillae, antecubital and popliteal fossae, and groin folds We have Aim - done this to study the prevalence, clinico-demographic and etiological prole of patients presenting with AN and to draw relations if any, with Coronary heart disease (CHD). It was an observational, descriptive, institution bas Materials and methods- ed cross-sectional study and was conducted over a period of 18 months at the out patient department (OPD) of Dermatology, Venereology and Leprosy of A tertiary care hospital in Eastern part of India, Anattempt was made to detect etiological factor of the disease by noting the temporal association between the disease and any systemic associations with special attention to CHD. Majority of Results- our patients had high BMI(69%). Six patients had systolic hypertension( RR- 11.5000 and p was .0002) and diastolic hypertension in 12 patients (RR- 5.7500, p value- P<0.0001). So patients with AN, who have high BMI are more prone to develop hypertension, the most important criteria for Coronary Heart Disease. In AN , high BMI Conclusionhigh triglycerides , high total cholesterol was signicantly associated with systolic hypertension, but there is no signicant association of LDL with any of systolic or diastolic hypertension.