Abstract
Objective: Candida albicans (CA) is one of leading cause leukorrhea due to microbial infection. Propolis wax is a fraction of propolis, and thus its remains as the side product of refined propolis are sufficient to inhibit CA, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus mutans growth. In this study, we used transparent solid soap containing Indonesian propolis wax to treated patients with leukorrhea disease.Methods: Quasi-Experimental designs that use for the Pre-Experimental design one group pretest-posttest design with a control group who performed on patients with leukorrhea in January 2014 in Tasikmalaya (West Java, Indonesia) district health center by using statistical analysis of T Test Dependent. The study conducted on 36 patients with leukorrhea and positively infected by CA. The transparent soap containing propolis wax 1% and 2% are used for to group I (20 respondents) and group II (10 respondents), and six respondents used as the negative control group.Results: The results showed that both groups could treat by the soap. The soap significantly effective in decreasing the number of CA, while six respondents in the control group showed a significant in increasing the number of CA. The results revealed that the content of propolis wax 1% and 2% in the preparation of transparent soap significantly influence on the subtraction of the number of patients with CA leukorrhea.Conclusion: The results obtained in this research work clearly indicated that the transparent soap containing propolis wax 1% and 2% have a potency to against leucorrhea disease caused by CA.
Highlights
About 75% of Indonesian women have experienced leukorrhea at least one time in her life, more than 70% of them caused by fungi, bacteria, and amoeba
It contrasts with European which only 25% are due to the humid weather in Indonesia caused infected by the fungus Candida albicans (CA), which is one cause of leukorrhea [1,2,3]
Leukorrhea caused by microbial infections, especially if occur in pregnant women
Summary
About 75% of Indonesian women have experienced leukorrhea at least one time in her life, more than 70% of them caused by fungi, bacteria, and amoeba. We performed a clinical study of the propolis wax in the solid soap in the ability to treat leukorrhea caused by CA. The result showed that the distribution data against the respondent with the provision of propolis wax treatment 1% seen that all colony of CA decreased after they treated by the soap
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