Abstract

Aggressive resuscitation in disease processes such as sepsis, peritonitis, and bowel ischemia can result in elevated intra-abdominal pressure (IAP), leading ultimately to abdominal compartment syndrome (ACS). Clinically, ACS causes organ dysfunction with oliguria, increased airway pressures, reduced oxygenation, and a fall in cardiac output (CO). There are currently no animal models that adequately mimic the complex pathophysiology associated with ACS. We have developed a clinically applicable porcine model that closely mimics the pathology seen in human patients.

Highlights

  • The aim of this study was to elucidate the impact of ICU-acquired infection on ICU and hospital mortality

  • The goal from this study is to evaluate weaning predictor indexes in patients during weaning from mechanical ventilation (MV)

  • This study aims to evaluate the effects of the threshold in such situations

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Summary

Introduction

The aim of this study was to elucidate the impact of ICU-acquired infection on ICU and hospital mortality. Methods A total of 48 community patients (36 men, 11 women, age 50.17 ± 17.974 years, APACHE II score 13.51 ± 6.153) who were expected to stay in the ICU for >5 days were included in this study. Specific examples of feedback are as follows: ‘good update of management plan reinforces need for taking into account concurrent medication when resuscitating patients’, ‘nice simple messages with good starting points for trying to deal with these complicated patients’, ‘useful data on risk of recurrence as this is a question often asked by patients’ This feedback was encouraging as it showed how the primary care professionals planned to change their practice to improve patient outcomes as a result of the learning. The course was considered excellent by 63% of the participants and good by 36%

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