Clinical value of the combined use of P-wave dispersion and troponin values to predict atrial fibrillation recurrence in patients with paroxysmal atrial fibrillation.

Abstract

P-wave dispersion (PWD) and cardiac troponin levels are independently associated with the recurrence of atrial fibrillation (AF) in patients with paroxysmal AF (PAF). We investigated the clinical usefulness of combining PWD and cardiac troponin I to predict AF recurrence in patients presenting to the emergency department with PAF. This study included 65 patients with PAF who were divided into three groups according to baseline troponin I and PWD values (group 1, troponin I<0.11 ng/dl and PWD<44.5 ms; group II, troponin I<0.11 ng/dl and PWD≥44.5 ms, or troponin I≥0.11 ng/dl and PWD<44.5 ms; group III, troponin I≥0.11 ng/dl and PWD≥44.5 ms). The AF recurrence rate was significantly higher in group III than in groups I and II. Multivariate analysis revealed that the troponin I and PWD values in group III (odds ratio: 7.236, 95% confidence interval: 1.879-27.861, p=0.004) were independent predictors of AF recurrence. The combined use of PWD and basal troponin I levels is a better predictor of AF recurrence than either value alone.