Abstract

Objective To investigate the clinical value of serum thyroglobulin (Tg) detection combined with SPECT/CT fusion imaging in the diagnosis of metastatic thyroid carcinoma. Methods 165 patients with differentiated thyroid cancer (DTC) undergoing total thyroidectomy in our hospital during Mar. 2012 to Apr. 2016 received the examination of serum Tg before the treatment with 131I. After a week’s treatment, they received the whole body scan and SPECT/CT fusion imaging detection. Through the combination of lymph node biopsy and clinical follow-up, determined whether the cervical lymph node metastasis. Results Lymph node metastasis occurred in 80 patients. The sensitivity of SPECT/CT detection was significantly higher than that of serum Tg (χ2=17.32, P<0.05), the sensitivity of combined diagnosis was significantly higher than that of SPECT/CT detection (χ2=5.71, P<0.05). Conclusion In lymph node metastasis of DTC patients, SPECT/CT detection combined with serum Tg detection can help to improve the diagnostic sensitivity of DTC lymph node metastasis, which is worth to be widely used in clinical. Key words: Thyroglobulin; Differentiated thyroid cancer; Single photon emission computed tomography

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