Clinical value of procalcitonin in early diagnosis of prostoperative urosepsis after percutaneous nephrolithotomy

Abstract

Objective By detecting procalcitonin level change, to analysis the clinical value of procalcitonin in early diagnosis of postoperative urosepsis after percutaneous nephrolithotomy(PCNL). Methods Eight hundred and seventy-six patients underwent percutaneous nephrolithotomy of the upper urinary stones were divided into two groups, 56 cases of postoperative urosepsis in observation group (PCNL), 820 cases in control group. Preoperative and postoperative 6 h PCT level of two groups were compared and analyzed. Results Two groups were completed smoothly PCNL. Preoperative PCT of observation group was (0.024±0.006) ng/mL, and postoperative 6 h PCT was (5.21±2.22)ng/mL, preoperative PCT of control group was (0.026±0.007) ng/mL, postoperative 6 h PCT was (1.31±0.29) ng/mL, Preoperative PCT levels of two groups were in normal range, there was no statistically significant difference between the two groups(P>0.05). Comparison of postoperative PCT before and after operation in two group was different degree rise, the differences were statistically significant(P<0.05), after 6 h PCT of two groups was compared, difference was statistically significant(P<0.05). Conclusions PCT levels of patients with suspected secondary sepsis after PCNL are detected , which will help to the early clinical diagnosis of urinary sepsis. Key words: Toxemia; Calcitonin; Nephrostomy, Percutaneous