Clinical value of of serum procalcitonin and high-sensitivity C-reactive in diagnosis and treatment of neonatal pneumonia and sepsis

Abstract

Objective To investigate the clinical value of serum procalcitonin and high-sensitivity C-reactive in diagnosis and treatment of neonatal pneumonia and sepsis. Methods From May 31th, 2014 to February 1st, 2016, 140 cases of neonatal pneumonia sepsis were given detailed discussion and analysis. The 140 patients with neonatal sepsis were divided into three groups by pneumonia sepsis hierarchical classification, the sepsis group, severe sepsis group and septic shock group. The PCT, hs-CRP levels and APACHEII scores were observed. Results The PCT, hs-CRP levels and APACHEII scores in the sepsis group were significantly lower than those in the severe sepsis group and septic shock group, the differences were significant (P<0.05). After referral, the serum PCT level was positively correlated with the hs-CRP level, and the APACHEII score in the sepsis group. Conclusions The PCT, hs-CRP level can determine the severity of the patient with neonatal pneumonia and sepsis. Meanwhile, after referral, The PCT and hs-CRP levels has important value in the efficacy observation and prognosis judgement, so it is worthy of promotion and use in clinical diagnosis and treatment. Key words: Neonatal pneumonia and sepsis; Serum procalcitonin; High-sensitivity C-reactive protein