Clinical value of immunochemical fecal occult blood test in diagnosis of colorectal diseases

Abstract

Objective To discuss the value of immunochemical fecal occult blood test (IFOBT) in diagnosis of colorectal diseases.Methods Two hundred and fifty-one patients who taken IFOBT and chemical fecal occult blood test (CFOBT) from January 2008 to August 2011 were enrolled in this study.They were definitely diagnosed by total colonoscopy combined with pathology.Results The positive rate of IFOBT and CFOBT in colorectal cancer patients was 100.0％ (57/57) and 84.2％ (48/57),there was significant difference (P ＜ 0.05).The positive rate of IFOBT and CFOBT in colorectal polyp patients was 38.6％ (32/83) and 10.8％(9/83 ),there was significant difference(P ＜ 0.05 ).The positive rate of IFOBT and CFOBT in inflammatory bowel disease patients was 100.0％ (31/31) and 80.6％ (25/31),there was no significant difference (P ＞ 0.05).The positive rate of IFOBT and CFOBT in non-specific enteritis patients were 86.8％ (33/38) and 73.7％ (28/38),there was no significant difference (P ＞ 0.05 ).The positive rate of IFOBT and CFOBT in normal colorectal cases was 2.4％ (1/42) and 19.0％ (8/42),there was siguificant difference (P ＜ 0.05).Conclusions IFOBT is better than CFOBT in diagnosis of colorectal cancer and colorectal polyp.IFOBT has lower false positive rate. Key words: Colonic diseases; Colorectal neoplasms; Immunochemical fecal occult blood test