Abstract
Objective To evaluate the potential clinical utility of T2 quantitative mapping for myocardial edema in acute disease pathology - myocarditis, myocardial infarction, TakoTsubo cardiomyopathy, and transplant rejection. Background Edema is ag eneric tissue response to acute myocardial injury and, therefore; a potential marker of impending tissue damage. Currently in clinical use, T2 weighted imaging provides a qualitative technique in assessing myocardial edema. We hypothesize that quantitative T2 mapping in patients with suspected cases of myocarditis, myocardial infarction (AMI), and cardiac transplant rejection will provide a more sensitive and specific diagnostic prediction than with T2W imaging, and add to other imaging techniques. Method
Highlights
Edema is a generic tissue response to acute myocardial injury and, ; a potential marker of impending tissue damage
We used a non-contrast multiplanar single-shot and cine TrueFISP and steady state free precession (SSFP) sequence developed by Siemens Healthcare which consists of T2-prepared, linear flip angle series of 20, 60, and 90 degrees, and SSFP readout
Regions of interest (ROI) based on the 17 segment myocardial model were drawn by two blinded reviewers (AU and MW) for inter-rater and intra-rater reliability
Summary
Clinical utility of cardiac magnetic resonance T2 mapping for acute myocardial edema. Asad A Usman*, Marie Wasielewski, Jeremy D Collins, Mauricio S Galizia, Andrada R Popescu, James C Carr. From 2011 SCMR/Euro CMR Joint Scientific Sessions Nice, France. From 2011 SCMR/Euro CMR Joint Scientific Sessions Nice, France. 3-6 February 2011
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