Abstract

IntroductionThe purpose of this short communication is to draw attention to an efficient design for trials to evaluate desensitising agents, and an appropriate statistical analysis. MethodsTwo recent sensitivity trials conducted by the Bristol Dental School Clinical Trials Group are reviewed. ResultsThe methodology used was effective to establish efficacy of the products evaluated. ConclusionsThis methodology is recommended for wider use. Clinical SignificanceEffective clinical trial methodology enables establishment of efficacy of desensitising products leading to patient benefit.

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