Abstract
A controlled clinical trial was conducted to test the effectiveness of gamma-globulin in the treatment of acute infections in children under the age of 2 years. A total of 102 children with acute infections were divided by random selection into three treatment groups: patients in the first group received gamma-globulin 0.2 ml/lb, in the second group 0.1 ml/lb, and the third group which received no gamma-globulin, served as controls. The three groups were comparable with respect to age, sex, length of illness and diagnoses. The administration of gamma-globulin to the two treatment groups did not affect the recovery time as compared with the controls. The presence of physiologic hypogamma-globulinemia in the early months of life was confirmed, and a steady increase in level of gamma-globulin was demonstrated with increasing age. In this series there was a statistically higher incidence of severe infections in infants under 6 months of age. Patients with severe in infections recovered more slowly than those with mild infections. No correlation was found between recovery time the age of the patient or the initial level of gamma-globulin. In those children 13 to 24 months of age there was a statistically significant correlation between initial level of gamma-globulin and the history of previous infection.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
