Clinical trial on standardised celandine extract in patients with functional epigastric complaints: results of a placebo-controlled double-blind trial

Abstract

The efficacy and tolerance of standardised celandine extract in the form of Gallopas 100 film-coated tablets were investigated in a placebo-controlled, double-blind trial on groups of 30 patients with functional epigastric complaints. Over the 6 week observation period, the only improvement in clinical findings was noted during treatment with the active drug. The distribution of the test findings showed a trend towards freedom from symptoms on Gallopas 100 for most of the symptoms. It was particularly noticeable that doctor and patients regarded the active medication as better tolerated than placebo. Inferential statistics validated the differences between Gallopas 100 and placebo in terms of efficacy and tolerance in respect of disorders of the gallbladder, biliary tract and pancreas.