Clinical treatment and follow-up of the first critical cases of critical rift valley fever in China

Abstract

Objective To investigate the treatment of the first case of rift valley fever in China. Methods The clinical data, treatments, prognosis and follow up data of the first case of rift valley fever in China were analyzed, retrospectively. Results This case of rift valley fever critically ill patient was male, 45 years old, living in Angela for 2 years, there were no rift valley fever epidemic. The main clinical manifestations were fever, headache, abdominal muscle pain, progressive reduction in urine output. Laboratory tests suggested severe liver and kidney function damage. On the third day of admission, the rift valley fever virus was reported positive by the Chinese CDC, and other pathogens were negative and rift valley fever was confirmed. After continuous blood purification, liver protection, stable cell membrane and symptomatic support treatment, the urine output was gradually increased, liver and kidney function gradually recovered. Outpatient follow-up for six months, liver and kidney function of the case were normal, and the patient was discharged. Conclusions As a zoonotic disease, the risk of rift valley fever incoming to China is gradually increased. Acute renal failure and acute liver injury are the main manifestations of critical rift valley fever, it could be effectively controlled after treatment. Key words: Imported transmitted diseases; Rift valley fever; Critically ill; Acute renal failure; Acute liver injury