Abstract
Diabetic Kidney Disease is now a worldwide health crisis. It is a spectrum of different pathophysiologic processes associated with abnormal kidney function and a progressive decline in glomerular filtration rate. Globally it is the 12th cause of death and 17th cause of disability. Clinically this condition can be correlated to Madumeha and Mutrakshaya. The present study focuses on the efficacy of the Poly herbo-mineral compound, Eladi Churna in the nephroprotective effect in DKD. Consent from all the selected patients was taken before the study. Ethical clearance was accredited by the Government Ayurvedic college and Hospital, Guwahati Assam and CTRI registration was done for the trial. The patients were given the trial drug 1gm twice daily after food with Tandulodak 25 ml and Swadangstradi kwath 25 ml as Anupana for 3 months. A marked improvement was found in eGFR, Serum Creatinine, Blood Urea and Urine Albumin levels. Satisfactory results were noted in chief complaints like urine output, oedema, nausea, vomiting and muscle cramps and Serum Uric acid level. No change was observed in Serum Sodium and Serum Potassium levels at the end of the course.
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