Abstract
To study the clinical effect of Huayu Tongluo Decoction combined with edaravone injection in the treatment of patients with acute cerebral infarction.86 patients with acute cerebral infarction received from our hospital from October 2016 to May 2018 were randomly divided into study group (n=43) and control group (n=43). Routine treatment was performed in both groups. On the basis of this, the control group was treated with edaravone injection, and the research group was treated with Huayu Tongluo Decoction combined with edaravone injection. The effects of treatment, the degree of neurological deficit (NIHSS score), TCM syndrome scores and quality of life (QLI score) before and after treatment were compared. The total effective rate of the study group [95.35% (41/43)] was higher than that of the control group [79.07% (34/43)] (P<0.05). After treatment, the main symptoms, secondary diseases and tongue and pulse of the two groups were treated. The scores were lower than before treatment, and the study group was lower than the control group (P<0.05). After treatment, the NIHSS and QLI scores of the two groups were better than before treatment, and the NIHSS score of the study group was lower than that of the control group, and the QLI score was higher than the control. Group (P<0.05). The clinical effect of Huayu Tongluo Decoction combined with edaravone injection in the treatment of patients with acute cerebral infarction is significant, which can further improve the clinical symptoms, improve neurological function and improve the quality of life.
Highlights
Cerebral infarction is a clinical multi-encephalic vascular disease, and its incidence accounts for about 75% of all cerebrovascular diseases, which can cause serious damage to the patient's nerve cells, resulting in high disability and mortality [1]
After the onset of cerebral infarction, the brain tissue is in an ischemic and hypoxic state, and the energy metabolism is abnormal, resulting in the mass production of oxygen free radicals, which can aggravate the damage of brain tissue and nerve cells
Huayu Tongluo Decoction consists of traditional Chinese medicines such as Salvia miltiorrhiza, Rhubarb, Pinellia, Tianma, Sichuan Achyranthes, Poria, Chenpi, Shengbai, Zhishi, Dannanxing, Tianzhuhuang, silkworm, and licorice [7]
Summary
Cerebral infarction is a clinical multi-encephalic vascular disease, and its incidence accounts for about 75% of all cerebrovascular diseases, which can cause serious damage to the patient's nerve cells, resulting in high disability and mortality [1]. The clinical use of statins, neurotrophic agents and antiplatelet drugs in the treatment of acute cerebral infarction, combined with free radical scavengers, can alleviate clinical symptoms to a certain extent, promote the recovery of neurological function, but the overall efficacy is not ideal [ 2]. The combination of traditional Chinese and Western medicine has been gradually applied to the treatment of cerebral infarction, and the role of traditional Chinese medicine in promoting neurological improvement has gradually received clinical attention [3]. This study selected 86 patients with acute cerebral infarction in our hospital, and studied the clinical effects of Huayu Tongluo Decoction combined with edaravone injection.
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