Abstract

The exudative constitution (hypersensitivity of skin and mucous membrane) is much observed in infant stage, showing hypersensitive reactions of skin and mucous membrane to the environmental stimuli, very often together with the resultant physical disturbance.The author, first of all, attributed the changes of hypersensitive phenomena of the skin and mucous membran originated from the outer stratum of embryo, to the changes or reduction in the Vitamin A content, as a nutritional factor.Since Vitamin A plays a dominant role in the growth of the combined tissue such as skin and mucous membrane, a clinical, biochemical study was made, and the results are briefly reported as follows:(A) After statistical observations of exudative constitution in infants, 1) The morbidity was 26 per cent in rural districta as compared with 18 per cent in urban communties.2) Even in rural districts, the morbidity was 50.5 per cent in cases of farming (including dairying) families as compared with 28.2 per cent in cases of salaried classes such as instructors, public servants as well as company and 1 or factory employees.3) The ratio of physical changes of skin to those of mucous membrane was 1: 0.79 in cases of suburban districts including farming villages, as compared with that of 1: 1.62 in urban areas-which implies more skin changes in rural districts.(B) With respect to the biological examination of nursing mothers and their infants, 1) Vitamin A content of the nursing mother's milk showed a higher decreasing tendency in the infants with advanced symptoms, 2) Vitamin A content of the suckling mother's blood sera showed a higher decreasing tendency in the infants with advanced disturbance of skin and mucous membrane.3) Vitamin A content of the infant's blood sera showed a higher decreasing tendency in the infants with advanced disturbance of skin and mucous membrane, the correlation coefficient being 0.382.From the above-mentioned observations, it is concluded that exudative constitution is found more in rural districts and that the more of such tendency is found, the more tendency of Vitamin A content decline.In addition, the results of internal and ointmental application of Vitamin A to such cases are now being observed.(The author wishes his deep graditude to the kind subsudy donated by Hokkaido Rural Medicine Association for this research, continously three times, in the years of 1971, 1972 and 1973).

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.