Abstract

Objective To study the quantitative analysis of myocardial reperfusion after percutaneous coronary intervention (PCI) using myocardial contrast echocardiography (MCE) in patients with coronary diseases. Methods The contrast agent of SonoVue via vein route using contrast pulse sequencing (CPS)MCE were performed in 15 patients with coronary diseases before and after the PCI. The intensity of amplitude (A) ,slope(β), A ×β, the contrast arrival times (AT) and the arrival peak times (TTP) were calculated with the autotracking contrast quantification software. Results Clear images of the left ventricle were well displayed in all the patients. There were satisfied images in the normal perfusion area of the myocardium,but not in the abnormal. AT,TTP and A ×β were significantly different between the abnormal and the normal perfusion area ( P <0. 05). The myocardial reperfusion significantly increased in the group that the coronary stenosis was greater than 70% after PCI( P <0. 05). There was no change in the group that the coronary stenosis was less than 70% ( P > 0.05). Conclusions PCI can efficiently improve the myocardial microcirculation. MCE can accurately, rapidly, and efficiently reveal the reperfusion status of myocardium after PCI. Key words: Echocardiography; Microbubbles; Coronary disease

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