Clinical study on the application of individualize d laser photocoagulation in Moderate Nonproliferative Diabetic Retinopathy

Abstract

Objective To explore the effects of retinal function with individualized diabetic retinopathy laser photocoagulation which guided by the FFA (Fundus fluorescein angiography) computer image information. Methods Sixty cases (110eyes) with indications of laser therapy moderate non-proliferative diabetic retinopathy according to the different methods were randomly divided into two groups, each group had 30 cases. Individualized laser photocoagulation with guided by the FFA computer image information was performed on the experimental group and pan retinal photocoagulation (PRP) by the traditional FFA image was performed on the control group. The follow-up was 24 weeks. Evaluation of degree of retinal damage was performed by retinal light sensitivity changes. Results Retinal light sensitivity was reduced by laser photocoagulation in the experimental group and control group. It was significantly lower in the experimental group that decreased 1.23± 0.47dB than in the control group (P＜0.05) that decreased 2.88± 0.68 dB. There was no significant difference on macular edema, neovascularization, visual acuity, capillary nonperfusion, postoperative complications between two groups in follow-up (P＞0.05). Conclusions Individual methods can effectively achieve the purpose of retinal laser photocoagulation therapy and the retinal dysfunction significantly less than the PRP group. Application of individualized laser photocoagulation treatments has no significant increase the risk of visual loss and other complications in the short term in moderate nonproliferative diabetic retinopathy. Key words: Computer information guided; Diabetic retinopathy; Laser photocoagulation; Individual treatment