Clinical study on laparoscopic cold cycle microwave ablation combined with hepatectomy for the treatment of hepatic hemangioma

Abstract

Objective To explore the clinical effect and feasibility of cold cycle microwave ablation combined with laparoscopic hepatectomy for hepatic hemangioma. Methods Thirteen cases of hepatic hemangiomas were treated with cold cycle microwave ablation combined with laparoscopic hepatictomy, and their clinical data were analyzed retrospectively from March 2015 to October 2017 in the First People′s Hospital of Jiangxia District of Wuhan City, including 5 males and 8 females with an average age of 52 years and age range of 45-68 years. The course of disease was 18 months to 8 years, with an average of 4.2 years. The clinical data were retrospectively analyzed and the operation time, intraoperative blood loss, postoperative hospital stay, liver function changes and complications were recorded. The data were analyzed using SPSS 17.0 statistical software, and measurement data with normal distribution were expressed as mean±standard deviation (Mean±SD). Results The operations of the 13 cases were successful, including 7 cases of single hepatic hemangioma (the lesions were located in segments Ⅱ, Ⅲ and Ⅳ) and 6 cases of multiple hepatic hemangioma (the lesions were located in segments Ⅱ, Ⅲ, Ⅳ, Ⅶ and Ⅷ). No hepatic portal occlusion was performed during the operation. The operation time was (135.4±35.8) min, intraoperative blood loss was (95.2±22.7) ml, the postoperative hospital stay was (6.4±0.8) d. On the first postoperative day, alanine aminotransferase was (354.2±75.4) IU/L, and aspartate aminotransferase was (382.7±68.5) IU/L, during the first week after surgery, alanine aminotransferase and aspartate aminotransferase both decreased to the normal range, and no serious complications such as bile leakage or hemorrhage occurred after surgery. No recurrence was observed after 6 to 12 months of follow-up. Conclusions Under the premise of strict control of surgical indications, laparoscopic cold-circulation microwave ablation combined with hepatectomy for hepatic hemangioma is safe and feasible. It can simultaneously treat multiple lesions, and cold-cycle microwave ablation can effectively reduce intraoperative bleeding with a minimally invasive effect. Key words: Microwaves; Ablation techniques; Hemangioma; Laparoscopes; Hepatectomy