Clinical study of single stent-assisted coiling of multiple intracranial aneurysms using low-profile visualized intraluminal support (LVIS)

Abstract

Objective To explore the safety and efficacy of single low-profile visualized intraluminal support(LVIS)-assisted coiling of multiple intracranial aneurysms. Methods Retrospective analysis of clinical data and radiographic data of 19 patients, who underwent one-stage aneurysm embolization of two intracranial aneurysms with single LVIS stent in the period from October 2014 to April 2016 at Department of Neurosurgery, Affiliated Hospital of Southwest Medical University. Results Nineteen patients were performed with stent-assisted coiling of multiple aneurysms using single LVIS. The average 11-month follow-up showed that good outcome (mRS: 0~1) was reported in 79% (15/19) of the cases. Mild disability (mRS: 2~3) was observed in 21% (4/19) of the cases. No severe disability or death occurred. Six-month follow-up showed that complete embolization rate was 87% (33/38)assessed using DSA and nearly complete embolization rate was 13% (5/38). A total of 4 aneurysms showed further progressed thrombosis during follow-up, and the incidence of further thrombosis was 57% (4/7)in patients with incomplete embolization. Intraoperative complications occurred in 3 patients which included 1 case of intraoperative rupture, 1 case of transient brain swelling and 1 case of intraoperative stent thrombosis. Conclusions Single stent-assisted coiling of multiple intracranial aneurysms using LVIS seemed to demonstrate safety and efficacy. However, the chance of symptomatic stent thrombosis could not be ignored. Key words: Intracranial aneurysm; Stents; Embolization, therapeutic; Treatment outcome