Abstract
：Objective To assessright ventricular(RV) global longitudinal function in patients with pulmonary arterialhypertension (PAH) by 2-dimensional ultrasound speckle tracking imaging (STI). MethodsAccording to pulmonary artery systolic pressure, 42 patients with PAH were divided intomild (17) ,moderate(15) and severe(10) PAH groups. RV global longitudinal peak systolicstrain (GLS), strain rate(GLSRs) ,early diastolic strain rate (GLSRe) and late diastolicstrain rate (GLSRa) were measured in 42 patients with PAH and 31 healthy controls by STIfrom the apical 4-chamber view and compared between groups and assessed the determinantsof the RV global longitudinal functional parameters. Results Right ventricularGLS,GLSRs,GLSRe, GLSRa were significantly impaired in patients with PAH compared withcontrols (P 0.05).Pulmonary vascular resistance and pulmonary artery systolic pressure were the determinantsof RV global longitudinal systolic function(r= - 0.466～- 0. 549, r = - 0. 403～- 0.425, respectively, P <0.05 for both). There were good correlations between tricuspidannular systolic peak velocity and RV GLS,GLSRs in patients with PAH (r = 0. 556～0. 585, P < 0.001).Conclusions RV global function decreases in patients with PAH, RV global longitudinalfunction can be accurately and objectively studied by STI. Key words: Echocardiography; Hypertension, pulmonary; Ventricularfunction, right; Speckle tracking
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