Clinical study of pulsed dye laser fine therapy for hypertrophic scar

Abstract

Objective To compare the efficacy and safety of pulsed dye laser with different parameters in the treatment of hypertrophic scar after burn. Methods From January 2016 to June 2016, 122 patients with hypertrophic scar after burn were treated in our unit. The data were analyzed retrospectively. According to the pulse width and energy of pulsed dye laser treatment, there were 31 cases with 0.45 ms-low energy, 28 cases with 0.45 ms-high energy, 37 cases with 1.5 ms-low energy and 26 cases with 1.5 ms-high energy, which were treated once every 3-4 weeks. The Vancouver Scar Scale (VSS) was used to evaluate the scar condition before and after treatment, and the pain of patients was scored by VAS before and after treatment. The blood flow of scar site was monitored before and 12 months after treatment, and the blood perfusion was recorded. The patients′satisfaction was recorded 3 to 6 months after treatment, and the satisfaction rate was calculated. Results ⑴ The VSS scores of 0.45 ms-low energy, 0.45 ms-high energy, 1.5 ms-low energy and 1.5 ms-high energy groups after treatment were significantly lower than those before treatment in each group (t=11.3, 9.0, 14.1, 12.7, P 0.05), but there was significant difference in the effect of other treatment groups(t=7.29, 4.81, 6.91, 5.11, 4.74, P 0.05). Conclusions The therapeutic effect of pulsed dye laser on hypertrophic scar is very exact, and the treatment parameters of 0.45 ms pulse width and low energy 4-6 J/cm2 are recommended, which provide clinical basis for the prevention and treatment of scar and the application of pulsed dye laser. It is worthy of clinical application. Key words: Cicatrix, hypertrophic; Lasers, dye; Laser therapy