Abstract
Objective To investigate the effects of endoscopic mucosal resection(EMR) and argon plasma coagulation(APC) on gastric mucosa prolapse(GMP).Methods One hundred and thirteen patients with gastric mucosa prolapse diagnosed by gastroscopy were randomly divided into standard EMR group(n =40),APC group(n =40) and control group (n =33).All patients had medical therapy for 4 weeks.These patients were followed up for the changes of symptoms and gastroscopy after 1 month,and the effect was evaluated.Results Compared with control group (32.26％),the total symptom relieve effective rate of standard EMR group (94.87％) and APC group (90.00％) was higher (P ＜ 0.01).But there was no significant difference in total symptom relieve effective rate between EMR group and APC group (P ＞0.05).Compared with control group(16.7％),the total effective rate by gastroscopy reexamination of standard EMR group (97.37％) and APC group (91.89％)was higher (P ＜0.01).But there was no significant difference in total effective rate by gastroscopy reexamination between EMR group and APC group (P ＞ 0.05).The proportion rate of endoscopic curative effect in EMR group (92.11％) was significantly higher than that in APC group (72.97％) (P ＜0.01).Conehsions Standard EMR treatment of gastric mucosa prolapse is a safe and effective minimally invasive treatment method. Key words: Endoscopic mucosal resection; Argon plasma coagulation; Gastric mucosa prolapse
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