Clinical Study of FS-LASIK with the Triple-A Profile for Super High Myopia Correction

Abstract

Objective: To investigate the visual and refractive outcomes in patients with super high myopia after thin-flap femtosecond laser assisted LASIK (FS-LASIK) combined Triple-A profile. Methods: In this prospective non-randomized case-controlled study, patients were enrolled from January to July 2016 at Affiliated Hospital of Nanjing University of Chinese Medicine, were divided into high myopia group (96 eyes of 48 patients) and super high myopia group (88 eyes of 44 patients). All patients were treated with FS-LASIK combined Triple-A profile. Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), spherical equivalent (SE) and high order aberration were measured preoperatively and 1 day, 1 week, and 1, 3 and 6 months postoperatively. Data were analyzed using repeated measurs ANOVA and generalized estimating equation. Results: At 1, 3 and 6 months after surgery, there was no significant difference between the two groups in the ratio of UCVA that was better than or equal to preoperative BCVA (P>0.05). At postoperative 6 months, there was no significant difference in the efficacy and safety index between the two groups (P>0.05). There was a hyperopic shift in the two groups after surgery. The shift was more significant in the super high myopia group in the early stage after surgery. The SE of the two groups tended to be stable after 3 months postoperatively. The changes in total corneal high order aberrations, spherical aberration and horizontal coma were significantly different in time and group, but there was no significant difference in vertical corneal aberration. Conclusions: The postoperative results indicate that using the Triple-A ablation profile of the MEL 90 excimer laser associated with thin-flaps is a safe, efficient, and predictable method to correct super high myopia. Key words: thin-flap; femtosecond laser; laser in situ keratomileusis; super high myopia; triple-A; visual quality