Abstract

Objective To investigate the clinical therapeutic effects of combination of shenshuaining capsule and ramipril on patients with chronic renal failure. Methods 100 cases of patients with chronic renal failure were randomly divided into treatment group (50 cases) and control group (50 cases). The patients in control group were administered ramipril 5 mg per day on the basis of conventional treatment; the patients in treatment group were administered Shenshuaining capsule 4 pills/d, ramipril 5 mg per day on the basis of conventional treatment. The laboratory parameters and clinical therapeutic effects of both groups were observed. Results Of the both groups, BUN, Scr and urine protein in patients with chronic renal failure were lower than those bofore treatment (P<0.05). Compared with the control group, the changes in treatment group were significant (P<0.05). The clinical symptomatic relief and therapeutic effects in treatment group were more significant than those in control group (P<0.05). Conclusion Compared with Ramipril, combination of shenshuaining capsule and ramipril can improve the renal function of patients with chronic renal failure, relieve their clinical symptom, and delay the progression of renal failure. Key words: Shenshuaining capsule; Ramipril; Chronic renal failure; Clinical therapeutic effects

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