Clinical studies on limbs’ refractory wound surface treated by platelet-rich plasma

Abstract

Objective To prepare platelet-rich plasma (PRP) for the treatment of extremities refractory wounds, and to explore the PRP to promote the healing of exposed wounds of bones and tendons. Methods 31 patients with external wound surface of the bone and tendon of four limbs were treated with autologous PRP transplantation, and wound healing rate and wound healing time were observed. Results Among the 31 patients, 18 had direct healing, 13 had active granulation growth and wound healing of skin graft in the second stage. The wound healing rate was 100%, and the average healing time was 41 d. Conclusion Autologous PRP transplantation for the treatment of extremity refractory wounds can inhibit the growth of wound bacteria, effectively promote the repair of soft tissue defects and accelerate the healing of wounds of the bones and tendons of the four limbs. Key words: Platelet-rich plasma; Refractory wound surface; Healing