Clinical studies of serous C. trachomatis IgG titers with enzyme-linked immunosorbent assay (ELISA)

Abstract

We measured serum IgG antibody titers for C. trachomatis with enzyme-linked immunosorbent assay (ELISA) in patients of various urological infections, in normal male group, in normal female group, and in prostitutes.1) Serum IgG class antibody titers to C. trachomatis had a good correlation with micro-IF titers. ELISA was considered a valuable melthod for measurement of serous IgG antibody titers for C. trachomatis.2) In male patients with gonococcal urethritis (GU) and non-gonococcal urethritis (NGU), positive rate of ELISA absorbance value was 68% and 64% respectively. The value was not shown apparent difference in GU or NGU, and not done in positive or negative of C. trachomatis isolation.3) Positive rate of ELISA absorvance value was 23% in normal male group. In male persons with frepquent sexual intercourse to prostitutes but without episodes of definite urethritis, the value was apparently higher than that in normal male group. Those in all male children without UTI were negative.4) In prostitutes, positive rate of ELISA absorbance calue was 90%. and 52% of positive case shoed strong positive.We considered the infection of C. trachomatis were caused in a wide range, and prostitutes played the most important role of infectous source.