Clinical Spectrum and Resistance Profile of Staphylococcus Infections in a Peri Urban Tertiary Care Hospital

Madhuri Madhuri,Manisha Khandait,Sweta Jangra

doi:10.22207/jpam.15.4.39

Abstract

Staphylococcus may be evaluated to be a serious microorganism to colonizes and contaminate both the healthy and immuno-competent people in the community along with the hospitalized patients with decreased immunity. This bacterium has been commonly present on the skin and in the nasal cavity of the human body. In the particular sites the organisms may give rise to local diseases of the nose, urethra, vagina and gastrointestinal tract, skin however most of them are minor and not associated with any mortality. S. aureus as well as coagulase-negative staphylococcus which are gram-positive bacteria that lives on the upper respiratory, mouth and skin structure creation, are the possible element for nosocomial and opportunistic disease in humans as well as in animals. Major complications involved with staphylococcus involved SSI, bullous impetigo, skin & soft tissues infection, bacteremia, pulmonary infections etc. The situation is further complicated by methicillin resistance in staphylococcus. MRSA/MRCoNS are considered as the emerging cause of hospital-acquired infections. it is very necessary to quantify the load of infections in order to achieve good hospital infection control policies. Furthermore, the morbidity and mortality rate may also be reduced in the same manner.

Highlights

Staphylococcus which are gram- positive bacteria live on the upper respiratory, mouth and skin structure creation, are possible element for nosocomial and opportunistic disease
S. aureus as well as coagulase negative staphylococcus which are gram- positive bacteria that lives on the upper respiratory, mouth and skin structure creation, are the possible element for nosocomial and opportunistic disease in humans as well as in animals
Under normal circumstances S. aureus and coagulase negative staphylococcus (CoNS) does not cause any infection in the human subjects; yet, if they are permitted to go into an internal tissue & bloodstream, these organisms might be a causative agent for variety of potentially critical ailments.[3]

Summary

Introduction

Staphylococcus which are gram- positive bacteria live on the upper respiratory, mouth and skin structure creation, are possible element for nosocomial and opportunistic disease. Isolated in purulent fluid from an abscessed leg by Ogston in the 1880s, further retreat by Rosenbach.[1]. S. aureus and coagulase negative staphylococcus (CoNS) are ubiquitous in nature as well as found on the skin and mucous membranes (most often the nasal area) of the healthy individuals as normal human flora. Nasal epithelium is one the most ordinary locations for S. aureus colonization, while transfer on the axilla, perineum and other skin sites appears less often.[2] Under normal circumstances S. aureus and CoNS does not cause any infection in the human subjects; yet, if they are permitted to go into an internal tissue & bloodstream, these organisms might be a causative agent for variety of potentially critical ailments.[3]. In 1960s Methicillinresistant staphylococcus (MRS) or multidrugresistant staphylococcus strains were initially isolated.[4]

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