Clinical significance of transperineal biopsy of the prostate transition zone in the diagnosis of prostate cancer

Abstract

Urological diseases in Russia account for 10–12 % of the total morbidity of the population and are one of the reasons for the decline in the quality of life, disability and mortality. In the structure of urological pathology in men, inflammatory and neoplastic diseases of the prostate gland dominate, and therefore, their timely diagnosis is of particular relevance. Ultrasound-guided prostate biopsy is the standard and most important procedure for diagnosing prostate cancer. The aim of the study was to determine the clinical significance of transperineal biopsy of the prostate transition zone in the diagnosis of prostate cancer. Transperineal biopsy from the transition and peripheral zones of the prostate was performed in 769 patients (a biopsy from 10 points in 491 patients, and from 12 points in 278 patients); prostate cancer was diagnosed in 276 patients (35.9 %). The authors of the article showed that the rejection of routine biopsy sampling from the transition zone, with a simultaneous increase in the number of biopsy specimens obtained from the peripheral zone, will improve the sensitivity of prostate biopsy as a method for diagnosing cancer.