Abstract

Objective To explore the significance of pH and nitrite detection in exhaled breath condensate of patients with ventilator-associated pneumonia. Methods The study was conducted between June 2012 and December 2017. 40 patients with gastroesophageal reflux disease and ventilator-associated pneumonia were selected as the observation group, and 40 patients with gastroesophageal reflux disease without ventilator-associated pneumonia were selected as the control group. The pH and nitrite detection of exhaled breath condensate were performed in both groups. The detection results were observed and compared between the two groups. Results In patients with ventilator-associated pneumonia, NO2- increased in exhaled breath condensate, pH decreased, with statistically significant differences compared with patients without ventilator-associated pneumonia (P<0.05). Conclusion The detection of pH and nitrite in exhaled breath condensate can reflect the patients' body state to some extent, and distinguish patients with ventilator-associated pneumonia from patients without pneumonia, providing guidance for clinically accurate treatment. Key words: Exhaled breath condensate; pH; Nitrite; Ventilator-associated pneumonia; Detection significance

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