Abstract
Treatment of pustular skin diseases by methods of parenteral and local ointment application of penicillin does not provide the proper therapeutic effect in all cases. It is often necessary to observe that the introduction of even massive doses of penicillin is not able to significantly affect the painful process, and only replacing it with another antibiotic, for example, biomycin or streptomycin, can lead to the desired result. The explanation for this should be sought in the unequal sensitivity of the microbial flora to various antibiotics.
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