Clinical significance of 3.0T dynamic contrast-enhanced nuclear magnetic resonance imaging in elderly patients with prostate cancer

Abstract

Objective To explore clinical diagnosis significance of 3.0T dynamic contrast-enhanced nuclear magnetic resonance imaging(DCE-MRI) in elderly patients with prostate cancer(PC). Methods This study contained 45 patients, including 30 cases of PC and 15 cases of benign prostatic hyperplasia, diagnosed and treated in our hospital from January 2016 to January 2017. All patients underwent magnetic resonance imaging (MRI) and DCE-MRI examinations, whose results were compared with the pathological results. The volume transfer constant (Ktrans), rate constant (Kep), extravascular extracellular volume fraction (Ve) values of central gland non cancer area, peripheral non cancer area, prostate cancer area were measured, PC group were divided further according to the Gleason score ≤ 7 points, 8 points, 9 points, 10 points. Results The Ktrans, Kep and Ve values of central gland non cancer area were significantly different from those in peripheral non cancer area and prostate cancer area (P 0.05). Ktrans and Gleason scores had positive correlation in prostate cancer area (r=0.654, P<0.05). Conclusions 3.0T DCE-MRI provides an objective basis for diagnosis of elderly patients with prostate cancer. Key words: Prostatic Neoplasms; Magnetic Resonance Imaging; Aged