Clinical research on self-made negative pressure drainage with Nano-Silver dressing in surgical incision infection

Abstract

Objective To explore the clinical effects of the combination of the self-made negative pressure drainage and Nano-Silver dressings on postoperative infection of incision. Methods A total of 84 patients with post-operative incision infection in the First People's Hospital of Xiangtan City from January 2013 to December 2015 were selected and divided into the observation group and the control group with 42 cases in each by random number table method. The observation group was treated with self-made negative pressure device combined with Nano-Silver dressing at the early stage, while the control group was treated with iodoform gauze dressing. When the wound bed granulation grew well, the two groups were treated with calcium alginate dressing or two stage suture until healed. The inflammatory index, incision growth and therapeutic effect of the two groups were compared. Results A week after treatment, the white blood cell, C reactive protein, incisional pain score and the change cost of the observation group were (7.62±2.15) ×109/L, (19.33±23.46) mg/L, (2.83±0.82) and (570.13±33.88) Yuan, which were all lower than those of the control group, and the differences were statistically significant (t=2.592, 2.695, 7.497, 7.752; P<0.05) . 100% coverage time of the incisional granulation tissue in the observation group was (3.86±1.37) d, and the healing time of the whole incision was (12.02±2.80) d in the observation group, which were both lower than those in the control group, with statistical significance (t=12.669, 6.954; P<0.01) . Conclusions The self-made negative pressure device combined with Nano-Silver dressing is ideal for the treatment of postoperative incision infection, while improving the therapeutic effect of the patients, and reducing the healing time of the incision and the cost of changing the medicine. Key words: Surgical wound; Infection; Vacuum sealing drainage technique; Nano-Silver dressing