Clinical research on ophthalmic artery recanalization in treatment of monocular blind caused by facial and forehead injection of hyaluronic acid

Abstract

Objective: To evaluate the safety and efficacy of ophthalmic artery recanalization in treatment of monocular blind caused by facial and forehead injection of hyaluronic acid. Methods: Thirty monocular blind patients who had hyaluronic acid injections before had interventional recanalization from December 2015 to December 2016. It took 20~120 h from injection to hospital. The ophthalmic artery recanalization was performed by interventional recanalization, and the drugs and physical therapy were also used. The technical success rate, complications related to technique, recanalization of blood vessels, visual recovery, and recovery of ocular and eyelid movements were evaluated. Results: The success rate of ophthalmic artery interventional recanalization was 100% (30/30) . 1 month after operation, 5 of 30 patients obtained visual recovery, with recovery rate of 16.7% (5/30) , 7 of 30 patients obtained light perception, with recovery rate of 23.3% (7/30) . In all 30 patients, eyeball hemorrhage and eyelid paralysis disppeared, swelling loci of medicine injection dissipated, and skin was healed basically, fundus fluorenscein angiograhy showed retinal revascularization and obvious development. Conclusions: It is a safe, effective and efficient therapy of ophthalmic artery recanalization in the treatment of monocular blind caused by facial and forehead injection of hyaluronic acid. Ischemic damage of the eye muscle and its dominant nerve were gradually restored after recanalization. Because of the sensitivity of retina for ischemia injury, visual recovery can be more difficult. Visual recovery treatment is a slow and comprehensive treatment process in a variety of ways. Key words: Hyaluronic acid; Cosmetic injections; Blindness; Eye eyelid injury; Interventional recanalization; Hyaluronic acid dissolving enzyme