Clinical research on application of acute noninvasive positive pressure ventilation in treatment of acute respiratory failure

Abstract

Objective To explore the clinical application effect and value of acute noninvasive positive pressure ventilation (NPPV) in treatment of acute respiratory failure (ARF) in the emergency department.Methods 47 patients with ARF by all causes were divided into two groups,according to the order and whether they were willing to breathing machine treatment.24 patients in NPPV group,and standard therapy group with 23 cases,standard treatment group used the routine treatment,based on routine therapy in the breathing machine,NPPV group was treated with index of the mask breathing machine under connection assisted ventilation treatment.We observed both groups before and after treatment the heart rate (HR),respiratory rate (RR),carbon dioxide points pressure (PaCO2),oxygen and index (PaO2/FO2),pH value change,the treatment outcome.Results HR,RR,PaCO2,PaO2/FO2,and pH value examination results before treatment standard treatment group and group compared with those of NPPV there was no statistical difference (P＞0.05),two groups' HR,RR,PaCO2 2 h,treatment within 24 h before testing results and the treatment was down,PaO2/FO2,pH value rised,NPPV group above index before and after treatment there was statistical differences (P＜0.05),standard treatment group within 24 h PaCO2 only treatment,PaO2/FO2,pH value and treatment before there was statistical difference (P＜0.05).Standard treatment group had survival rate by 60.87％,the death rate 39.13％,and the average hospitalization time (24.45 ± 12.13) d,NPPV group survival rate by 87.50％,the death rate 22.50％,and the average hospitalization time (16.64 ± 9.87)d,two groups in the length of time and the survival rate of the patients,there was statistical significant difference (P＜0.05).Conclusion The acute NPPV application in treatment of ARF can quickly improve patients' ventilation condition,and increase their survival rate. Key words: Acute respiratory failure (ARF); Noninvasive positive pressure ventilation (NPPV); Emergency