Abstract
Abstract Background: Primary granulocytic sarcoma (GS) only rarely presents with an ovarian mass classified as extramedullary myeloid progenitor tumor cells. Few patients with cases of primary GS survive after systemic chemotherapy. Objective: To present a case of primary GS treated with complete course of chemotherapy. The patient is currently in complete remission. Methods: Retrospective review of medical records and comparison with previous case reports. Results: A 41-year-old woman presented with an ovarian mass of 6 months duration. There was no previous history of hematologic disease or presence of leukemic cells in other organs at the time of diagnosis. Immunohistochemistry confirmed the diagnosis. She received complete course of chemotherapy, after which complete remission was achieved. Conclusion: A case of primary granulocytic sarcoma of the ovary was successfully treated with chemotherapy. This disease needs careful diagnosis and appropriate treatment for a good outcome.
Highlights
Primary granulocytic sarcoma (GS) only rarely presents with an ovarian mass classified as extramedullary myeloid progenitor tumor cells
We report the case of a 41-year-old woman who presented with a right ovarian mass and abdominal distension
Cells of GS are thought to originate from intramedullary areas of the bone marrow spreading via the Haversian system throughout the entire body [5, 9]
Summary
Supat Chamnanchanunta, Chajchawan Nakhakesb, Pravinwan Thungthongb, Tawatchai Suwanbanb, Kunapa Iam-arunthaib, Napat Sukgasic, Maleerat Sutherata aDepartment of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, bDivision of Hematology, Department of Medicine, Rajavithi Hospital, Bangkok 10400, cInstitute of Pathology, Department of Medical Services, Ministry of Public Health, Nonthaburi 11000, Thailand
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