Abstract
SummaryThe interaction of nitrous oxide and vitamin B12 and its implications are not the exclusive territory of any one discipline. The initial discovery was by a chemist but it is of obvious relevance to anaesthetists and intensivists; some complications are neurological others haematological. The interaction provides an extremely important research tool as the first easily available B12‐deficient animal model. Finally there are implications for exposure to contaminated atmospheres in hospitals and in industry.
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