Abstract
THE COMPLEMENT DEPENDENT cytotoxicity test had been the only useful method to measure alloimmunization; its use before renal transplantation has become routine to predict the risk of graft failure. Recently, new more sensitive and specific techniques have been developed, to measure HLA antibodies, such as flow cytometry or ELISA. This development has led to renewed interest in the measurement of HLA antibodies after transplantation, which was not performed routinely. The aim of the present study was to determine the role of ELISA, an easy and sensitive method to recognize donor-specific anti-HLA antibodies (HLA Abs), in the monitoring of renal graft recipients after kidney transplantation.
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